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Palladia is a prescription-only veterinary anti-cancer medicine for dogs. It contains toceranib (as toceranib phosphate), a multi-kinase inhibitor used in the management of certain canine mast cell tumours as directed by a veterinarian.
Palladia tablets are indicated for the treatment of Patnaik grade II or III, recurrent, cutaneous mast cell tumours with or without regional lymph node involvement in dogs, when prescribed by a veterinarian.
Always follow your veterinarian’s directions and contact them promptly if your dog shows signs of adverse effects.
Palladia 50mg is an oral prescription tablet for dogs containing toceranib (as toceranib phosphate) at 50 mg per tablet. It is classified as a targeted anti-cancer therapy and must be used under veterinary direction.
Palladia is most commonly prescribed for recurrent, cutaneous mast cell tumours (Patnaik grade II or III), with or without regional lymph node involvement, when your veterinarian decides it is appropriate for your dog’s case.
Toceranib is a multi-kinase inhibitor. In practical terms, it can help slow tumour progression by interfering with signalling pathways involved in tumour cell growth and by reducing the development of blood vessels that support tumours (anti-angiogenic effect).
Many veterinarians and oncology services consider Palladia a form of anti-cancer therapy (often discussed alongside “chemotherapy”), but it is commonly described as a targeted therapy rather than a traditional cytotoxic chemotherapy drug. Your vet can explain how it fits into your dog’s treatment plan.
Palladia is often dosed on an every-other-day schedule, with the dose calculated from your dog’s bodyweight. Your veterinarian may adjust the dose, pause treatment, or reduce frequency based on response and side effects. Always follow the exact directions on your dog’s prescription label.
Palladia may be given with or without food unless your veterinarian instructs otherwise. Some dogs tolerate treatment better when medication is given with a small meal or treat.
Do not split or crush Palladia tablets unless your veterinarian specifically instructs you to do so. Splitting/crushing can increase exposure risk to humans and may affect how the dose is delivered. If dose precision is needed, your vet may prescribe a different tablet strength.
Follow your veterinarian’s instructions. In many cases, the guidance is to skip the missed dose and resume the next scheduled dose, rather than doubling up. Because Palladia is often dosed every other day, timing matters—check with your vet for your dog’s plan.
If vomiting occurs shortly after dosing, contact your veterinarian for advice before giving any extra medication. Your vet may recommend supportive care, timing changes, or dose adjustments depending on severity and frequency.
Side effects can include gastrointestinal upset (e.g., diarrhoea, vomiting, reduced appetite), lethargy, and changes seen on bloodwork (your vet may monitor for these). Not every dog experiences side effects, and many can be managed with veterinary support and dose adjustments.
Seek veterinary advice promptly if you notice: persistent vomiting, watery diarrhoea, black/tarry stools, fresh blood in stool or vomit, unusual bruising/bleeding, collapse, severe weakness, or anything that concerns you. These may indicate serious adverse effects that need urgent assessment.
Often, yes. Many dogs on Palladia have periodic veterinary check-ups and blood tests to monitor tolerability and guide dose modifications. Your vet will advise the most appropriate schedule for your dog.
Your veterinarian will determine suitability. Safety evaluations may be limited in very young dogs and dogs under a minimum bodyweight. If your dog is small or under 2 years of age, your vet will weigh benefits vs risks carefully.
Palladia can sometimes be used alongside other therapies, but interactions are possible. Always tell your veterinarian about all medications and supplements your dog is taking, including anti-inflammatories, steroids, flea/tick treatments, and herbal products. Your vet will decide what is appropriate and may adjust treatment to reduce risk.
Your veterinarian may use extra caution when Palladia is given with NSAIDs, because some combinations can increase the risk of gastrointestinal irritation or complications in certain dogs. Never add pain relief or anti-inflammatories without veterinary approval.
Palladia is generally not recommended for dogs used for breeding, or for pregnant/lactating bitches unless your veterinarian advises otherwise. Discuss pregnancy plans and breeding status with your vet before starting treatment.
Palladia is an anti-cancer medicine. Practical precautions can include: washing hands after handling tablets, using disposable gloves (especially for pregnant people or those trying to conceive), avoiding contact with children, and taking care when cleaning up urine, faeces, or vomit from treated dogs. Ask your veterinarian for household-specific advice.
Store at room temperature in the original container, tightly closed, away from heat and moisture. Keep out of reach of children and pets, and do not store alongside food items.
Yes. Palladia is supplied as a veterinary prescription medicine. To purchase, you will need a valid prescription issued by your veterinarian. Discount Pet Meds can only dispense Palladia once prescription requirements are met.
You can buy Palladia 50mg Tablets (30) online from Discount Pet Meds. Place your order on our website and follow the prescription process at checkout. If you need help ordering or uploading/sending your prescription, contact Discount Pet Meds and our team will assist.
Prescription medicine: This is a prescription medicine. Please ensure that you have read the "How to Order" page before ordering this item. Australian legislation prohibits the advertisement of prescription drugs to consumers, therefore we are unable to display any images of the packaging or provide you with more information regarding this prescription medicine.
Our prescription medicines: All prescription medicines on the Discount Pet Med site are purchased through Veterinary Wholesalers the same as those used by your Vet. All of our products are APVMA approved and identical to those used by your Veterinary Surgeon.
Product images: Australian legislation prohibits the advertisement of prescription drugs to consumers, therefore we are unable to display any images of the packaging or provide you with more information regarding this prescription medicine.
Please call or email us if you have any queries about any of the products on our site.
How much does shipping cost?
Your delivery cost starts from $6.95. This depends on the weight of your order, delivery address and delivery method (express vs standard). The shipping cost calculator will display the total cost for delivery at the checkout. We use live quote system powered by Australia Post; this guarantees you pay the lowest shipping fee.
How do I qualify for Free Delivery?
Discount Pet Meds offers Free Standard Shipping on orders over $149 Australia wide for parcels up to 500g. Orders over $149 and over 500g will receive a discount of $6.95 on total shipping cost which will is automatically applied during checkout.
Which shipping should I select?
Discount Pet Meds uses Australia Post as their courier partner, with two shipping options to select from at checkout:
Express Post the fastest choice
Standard Post the most economical (normally 2 days behind express post)
Please note: Australia Post has a weight limit of 22kg per parcel. If your order weighs over 22Kgs we recommend placing multiple orders or contact us to arrange for a courier
How long will it take to process my order?
Discount Pet Meds guarantee same day dispatch if your order is in-stock and has been placed before 11am weekday. In- stock items ordered after 11am, will be dispatched next business day.
Compounding Meds: Please allow extra 2 business days (eye drops: 5 business days)
How long will it take to receive my parcel?
In addition to processing and dispatch time at the warehouse (24-48 hrs), Delivery time will depend on where you are, in relation to our warehouse as we are based in Carlingford, Sydney, NSW.
The following are estimated delivery times once your order has been fulfilled and left our warehouse. These are only estimates and are dependent on mail services in your area.
Standard Post
Local/Sydney area: 1-2 business days
New South Wales: 2-3 business days
Brisbane: 2-3 business days
Melbourne: 2-3 business days
Adelaide: 3-5 business days
Perth: 3-5 business days
Queensland: 3-7 business days
Victoria: 3-7 business days
South Australia: 5-10 business days
Tasmania: 5-10 business days
Western Australia: 5-10 business days
Northern Territory: 5-10 business days
Express Post
Sydney area: next day delivery
Other Metro areas and Major cities: 1-3 business days
Rural areas: please allow up to 5 business days.
Do I need to stay home to receive my parcel?
All parcels will be delivered to the provided address and will require a signature on receipt, It is recommended to provide a work address for delivery if no one is home during business hours. If no one home, a card will be left detailing the nearest Australia Post outlet where the parcel can be collected during normal business hours.
Authority to Leave (ATL): Although we do not recommend leaving orders unattended when not home to accept delivery, you may request this service with any delivery. You may do this by placing a brief note, such as Please leave order if not home', in the order comments section found on our checkout page.
Australia Post (Safe Drop): Tracking notifications now provide you the possibility of Safe Drop where the order will be left in the Safe Drop location specified unless, in the judgement of the carrier, it is exposed to passers-by or the weather, in which the parcel will be carded for a Post Office collection
What if my order got delayed, lost, stolen or damaged?
Shipping insurance will allow you to be compensated in case of lost, damaged, or delayed delivery. If shipping insurance is not chosen, we will not be able to offer any further assistance if your order is lost or subsequently goes missing after it has been deemed delivered by the carrier. The associated risk in leaving parcels unattended is borne by the customer.
Refrigerated items: when you purchace a cold chain product, you accept the rare chance that goods will not be delivered in an ideal condition and that no compensation will be offered to replace spoilt goods, even if insurance cover is chosen.
How do you ship refrigerated items?
Fridge items are sent out Monday, Tuesday and Wednesday only, by Express Post in foam eskies containing ice Blocks, to ensure items remain cold on delivery. Please refer to the below link to see if you are within the Australia Post Express Network:
How do I track my order?
With email and SMS tracking notifications, you will get peace of mind to track and choose delivery options. You will be given a tracking number and the date your parcel is expected to be delivered, as well as the chance to choose how and where you like to receive it.
What if I want to Pick up my order?
Pick up is available from our store. Please select “Pickup option" at the checkout. We will contact you once your order has been assembled and is ready for collection.
Pick up address: 4/500 North Rocks Road Carlingford, Sydney NSW, 2118.
Can I refund medication after collection?
We can dispose your unwanted medication, but we can’t refund it. Once a prescription item leaves our pharmacy, by law they cannot be resold. As such, refunds are not possible.
